Diabetic Nephropathy: Pathophysiology and Clinical ManagementAbout This Hardback Diabetic nephropathy is a chronic loss of kidney function. It occurs in people suffering from diabetes mellitus. Due to the damage of glomeruli, it causes protein loss in the urine. It also causes low serum albumin that eventually results in nephrotic syndrome. The initial symptoms of diabetic nephropathy appear after five to ten years of its beginning. The first symptom includes nocturia, which is frequent urination at night.