Fat in your lungs? How vaping can impact your body's ability to fight viral respiratory infections. The Pipettepen Vaping vs Cigarettes Health Impacts Compared Vaping vs. Smoking: Health Risks and Long Term Effects AOI Toki Let's be real, what's the difference between vaping versus smoking cigarettes? We know that vaping contains no tobacco and far less chemicals than cigarettes but the keyword here is 'less'.